... that aortic distensibility is not impaired inpatientswith different forms of Chagas' disease, even in those with heart failure Our results observed inpatients without CHF coincide with those ... impaired in group that comprised patientswith systolic dysfunction Also, the peak VO2 was significantly decreased in group patientswith systolic dysfunction, in comparison with that inpatients without ... infiltrates and focus of myocarditis associated with focal fibrosis, with a variable intensity Experimentally, Chagas' disease causes vasculitis of the large arteries, affecting the muscular and endothelial...
... severe sepsis, in children with severe sepsis, and inpatients receiving lowdose heparin [3] In the Administration of Drotrecogin Alfa (Activated) in Early Stage Severe Sepsis (ADDRESS) study [1], ... time to treatment with DrotAA has an influence on mortality [9,10], with the maximum beneficial effect being observed if treatment is started within 24 hours of the onset of sepsis-induced organ ... lung injury/acute respiratory distress syndrome Recommendation We concur with the ADDRESS authors DrotAA should not be usedinpatientswith severe sepsis and low risk for death Competing interests...
... 16(SPSS Inc., Chicago, IL) Imam hospital is the main referral teaching hospital for HIV/ AIDS patientsin Iran The records of all patientswith TB /HIV co-infection admitted to the Infectious Disease ... seropositivity was confirmed by at least two positive ELISA tests followed by a positive western blot test as confirmations InHIV positive patients, tuberculin skin test ≥ mm and inHIV negative patients, ... or in other words, in those with high CD4 cell count Those with CD4 count less than 200, mostly show atypical CXR findings In addition, normal and traditional typical findings of tuberculosis...
... boosted regimen with Ritonavir Twenty-seven individuals were taking Tenofovir; 18 in combination with NNRTIs and with PIs Patients taking corticosteroids, suffering from Laboratory analysis Plasma ... bioavailability of vitamin D in obesity Am J Clin Nutr 2000, 72:690-693 Page of 38 Bischoff-Ferrari H: Health effects of vitamin D Dermatol Ther 2010, 23:23-30 39 Glare PA: Pain inpatientswithHIV infection: ... D: Greater decrease in bone mineral density with protease inhibitor regimens compared with nonnucleoside reverse transcriptase inhibitor regimens in HIV- 1 infected naive patients AIDS 2009, 27:817-824...
... from HIV- 1 infected patients, and its relationship with HIV- 1 viraemia Immunostaining was performed with fluorochrome-conjugated antibodies in 100 μl of peripheral blood from HIV- 1 infected patients ... NK cells bearing the CD94/NKG2A inhibitory receptor decreases in advanced HIV infection [8], in contrast with other inhibitory receptors of the KIR family which are upregulated Itis presently ... and HIV- 1 infected controls (viraemic and aviraemic) There was a dramatic decline in the proportion of CD8+ T cells expressing the CD94/NKG2A heterodimer in HIVinfected patientsin comparison with...
... Critical Care Vol 13 No Christaki implications of endotoxin tolerance continue to be elusive [4] Although endotoxin tolerance has been implicated in increased susceptibility to secondary infections, ... underlying dysregulations that contribute to the pathogenesis of VAP Although patientsin the two groups did not differ significantly in terms of age, disease severity, underlying conditions, ... Raftogiannis M, Zervakis D, Koussoulas V, Orfanos S, Kotanidou A, Armaganidis A, Roussos C, Giamarellou H: Early apoptosis of blood monocytes in the septic host: isit a mechanism of protection in the...
... treatment with methotrexate or tumor necrosis factor alpha inhibitors does not increase Epstein-Barr virus load inpatientswith rheumatoid arthritis Arthritis Rheum 2007, 57:762-767 Smets F, Latinne ... Kennedy LG, Whitelock H, Gaisford P, Calin A: A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index J Rheumatol 1994, 21:2286-2291 ... viral load and disease activity (Disease Activity Score for 28 joints for RA patients, P = 0.54; Bath Ankylosing Spondylitis Disease Activity Index for SpA patients, P = 0.84) or disease duration...
... system during the early development of PLE, rather than a causal factor However, reports of opportunistic infections inpatientswith PLE are rare [5,10] This finding isin agreement with our observation ... albumin, × 50 ml 20%/day), a single immunglobulin infusion (Sandoglobin®), C1-esterase-inhibitor (Berinert®) and prednisolon (3 × mg/day per orally; during the early phase, in addition, 10–20 mg intravenously) ... been missed on the biopsies, as proposed by others [3] 190 Finally, is an ‘infection hypothesis’ plausible for the development of PLE in Fontan patients? We speculate that itis All patients with...
... hours with or without operation 93.3 E Emergency operation because itis simple to calculate without requiring additional resources It may be surprising that itis predictive, as ASA scoring does ... assessing risk, there is a paucity of clinical studies showing how this has changed the management of either individual patients or groups of patients We hope that soon data will appear showing how ... possibilities of influencing change and costs Itis also interesting to compare the presented definitions with the various studies of ‘high risk’ surgical patients where different levels of risk...
... MEM in Portugal with emphasis on its efficiency in reducing response times and in evaluating patients where the need for immediate assistance was uncertain [4] One serious injury and two minor injuries ... MEM was not used after 10 PM in order to reduce the accident risk No injuries to the MEM paramedic were registered and this isin accordance with Portuguese results indicating 0.8 injuries pr ... medical interventions in 121 patients before the arrival of another ambulance Intravenous drugs were given in 63 cases, including 23 cases of naloxone administration to heroine intoxicated patients...
... health-focused quality of life even before the fracture occur [29-32] The wrist patients have a modest decrease in health-focused quality of life within physical domain and scores in accordance with ... diseases and conditions as well [56] However, our findings suggest that by identifying patientswith low GQOL, in addition to other known risk factors for hip fracture, may rise the probability ... develop and initiate prevention and rehabilitation efforts Conclusion This is the first study to compare GQOL inpatientswith a low-energy wrist fracture or hip fracture with GQOL scores in matched...
... Cell viability (%) A Without ascites With ascites * Without ascites With ascites * * * * * 10 TRAIL (ng/ml) 25 10 TRAIL (ng/ml) 25 Cell viability (%) 318A cells Without ascites With ascites * * ... prognosis potential of having protective ascites against TRAIL-induced CaOV3 cell death Protective ascites were arbitrarily defined as TRAIL IC50 with ascites/IC50 without ascites > 2-fold Clinical ... cancer ascites inhibit TRAIL- and FasL-induced apoptosis in vitro [10] In that study, six ovarian cancer ascites were tested and five out of six inhibited TRAIL-induced cell death, albeit to different...
... patientswith SLE as well as in 40% of patientswith mixed connective tissue disease, usually in association with other anti-spliceosomal autoAbs [8,9] The autoAb response against hnRNP-A2 shows ... for this antigen The data obtained suggest that hnRNP-A2 may constitute an important T cell autoantigen inpatientswith SLE, indicating a potential role for itin the pathogenesis of this disorder ... cultures with antigen to mean cpm obtained in cultures incubated in the absence of antigen An SI ≥3.0 and a ∆cpm >1,000 (mean cpm obtained in cultures with antigen minus mean cpm obtained in cultures...
... fluid neutrophil apoptosis was significantly lower inpatientswith RA than inpatientswith non-RA persistent synovitis (P = 0.0004) or inpatientswith resolving synovitis (P = 0.002) Results ... than at initial presentation in two of the 10 RA patients, six of the 11 patientswith non-RA persistent synovitis and four of the 11 patientswith resolving synovitis Prior therapy with a DMARD ... than at initial presentation in two of the seven RA patients, four of the 11 patientswith non-RA persistent synovitis, and seven of the 13 patientswith resolving synovitis Prior therapy with a...
... infection in our patientsin the best multiple logistic regression model This finding isin line with a previous study on major infections in SLE patientsin the Hopkins Lupus Cohort [32] Renal insufficiency ... deposition, and MBL pathway activity in three subgroups of patients: SLE patientswith one or more major infections, patientswith SLE who experienced minor infections only, and SLE patients without ... one infectious episode since lupus diagnosis in 50% of patientswith SLE, and this high infection rate is confirmed by other studies reporting infectious complications in up to 45% of SLE patients...
... overexpressed in inflamed synovial tissue, in particular in the lining layer and in sublining cells [9], and itis elevated in draining lymph from affected joints [10] Furthermore, IL-1β is localized ... time point during the study apy in RA in disease Reductionpatients activity and CRP levels following ACZ885 therapy in RA patients (a) Mean disease activity (Disease Activity Score using 28 joint ... binding of the two natural ligands, namely IL-1α and IL-1β As compared with TNF-α inhibitors, it appears that treatment with the recombinant IL-1Ra is less efficacious in RA [3] However, it is...
... leading to cachexia This finding isin accordance with the known difficulties of treating cachexia with diet However, recently supplements with amino acids have been shown to increase muscle mass ... this definition of rheumatoid cachexia to be used, as it verifies that itis associated with increased morbidity However, patients on a Mediterranean-like diet had high anti-PC levels in spite ... min), chronic obstructive lung disease with emphysema, earlier gastric ulcer or intestinal surgery, known eating disorder or steroid injections within weeks The patient characteristics are shown...
... file) Insulin resistance was evaluated from fasting glucose and insulin using the Homeostasis Model Assessment of Insulin Resistance (HOMA IR) [30] and the Quantitative Insulin Sensitivity Check Index ... insulin resistance and chronic kidney disease in nondiabetic patients, independent of other risk factors [64] Insulin resistance has also been described inpatientswith RA and may associate with ... Nightingale P, Douglas KM, Kitas GD: Cardiovascular risk factors and not disease activity, severity or therapy associate with renal dysfunction inpatientswith rheumatoid arthritis Ann Rheum Dis...
... with Hepatotoxicity in an HIV- Infected Individual J Infect Dis 2008, 197:932-933 doi:10.1186/1742-6405-8-9 Cite this article as: Esposito et al.: Management of HIV- 1 associated hepatitis inpatients ... this was observed in association with an immune recovery, suggesting the hypothesis of a pathogenetic role played by HIV- 1 infection in the liver damage Inpatientswith HIV- 1 disease there are ... were predominantly within the normal ranges, with only small increases due to occasional alcohol intake On September 2006, during a rescue treatment with atazanavir/ ritonavir, lamivudine and tenofovir,...